Author (year) Recruitment setting | Study information | Psychiatric comorbidity information | Intervention | Outcomes | ||||
---|---|---|---|---|---|---|---|---|
Intervention | Comparator | Duration | Anxiety | Outcome | Tolerability | |||
Stokes [19] Setting Specialty Clinic | Study design Randomized controlled trial Study population Chronic Enteritis or Ulcerative Colitis | Screening tool Hamilton Anxiety Rating Scale (HAM) Moderate to severe anxious mood, and 3 anxiety-related symptoms on HAM Global rating scaleModerate anxiety | Pharmacologic Lorazepam 1 mg QAM 2 mg QHS (n = 24) Provider delivering intervention Gastroenterologist | Placebo (n = 21) | 4 weeks | Hamilton Anxiety Rating Scale Lipman-Rickels 35-item Self-rating scale Global rating scale | Difference in mean scores | Discontinuation rate Rate of adverse effects |