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Table 2 Technical comparison of acute OL differentiation assay with other OL differentiation assays

From: A high throughput drug screening assay to identify compounds that promote oligodendrocyte differentiation using acutely dissociated and purified oligodendrocyte precursor cells

Technical details

MRF-TMCa

Deshmukh [3]

Mei [6]

Najm [7]

Pre-toxicity screen

   

Rat OPCs

 

Mouse OPCs

  

Acutely-derived

   

Passaged/expanded OPCs

 

 

iPSC-derived OPCs

   

Cortex-derived OPCs

 

 

Optic nerve-derived OPCs

 

  

MBP/PDGFRα/micropillar wrapping analysis

  

 

MBP expression analysis

 

  1. aMyelin Repair Foundation, Translation Medicine Center