Skip to main content

Table 1 List of contraindicated drug combinations and potential risk

From: Potential drug–drug interactions among elderly patients admitted to medical ward of Ayder Referral Hospital, Northern Ethiopia: a cross sectional study

Drug combinations Number of patients Documentationa Potential risks
Clarithromycin simvastatin 3 Good Increased risk of myopathy or rhabdomyolysis
Clarithromycin ciprofloxacin 1 Fair Increased risk of QT interval prolongation
Total 4   
  1. a Documentation based on available studies or reports: good, studies strongly suggest that the interaction exists except proof of well-controlled studies; fair, available evidences are poor, but the interaction is suspected on the basis of pharmacologic considerations; or, evidences are good for an interaction of pharmacologically similar drug [24]