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Table 2 Availability of data from trials registered at clinicaltrials.gov

From: Clinical trials registries are underused in the pregnancy and childbirth literature: a systematic review of the top 20 journals

Journal

Article name

Search string

# applicable clinical trials retrieved

# of trials which could have potentially been included in the systematic review

J Obstet Gynecol Neonatal Nurs

A systematic review of the effectiveness of breastfeeding intervention delivery methods

(Breastfeeding OR lactation OR breast milk) AND (e-technologies OR intervention OR technology OR technologies OR web-based)

1655

0

Matern Child Nutr

Association between timing of introducing solid foods and obesity in infancy and childhood: a systematic review

(Infant OR newborn OR childhood OR infancy OR neonate OR neonatal) AND (feeding OR food OR breast milk OR breastfeeding OR solid food) AND (body mass index OR BMI OR obesity OR weight)

775

6

BMC Pregnancy Childbirth

Caesarean delivery and subsequent pregnancy interval: a systematic review and meta-analysis

(Caesarean section OR Caesarean delivery OR abdominal delivery OR C-section) AND (birth interval OR birth spacing OR pregnancy interval OR first birth interval OR inter-delivery interval OR pregnancy gap OR pregnancy spacing)

37

2

Paediatr Perinat Epidemiol

Effect of women’s nutrition before and during early pregnancy on maternal and infant outcomes: a systematic review

(Early pregnancy OR gestation OR pregnancy OR early gestation) AND (nutrition OR women’s nutrition OR diet) AND (outcome OR birth OR birth outcome OR birth outcomes)

597

9

Am J Perinatol

Endothelial nitric oxide synthase gene polymorphisms and risk of preeclampsia

(Preeclampsia OR pregnancy-induced hypertension OR gestational hypertension) AND (endothelial nitric oxide synthase OR endothelial NOS OR nitric oxide synthase)

3

0

Birth Defects Res A Clin Mol Teratol

Folic acid–containing supplement consumption during pregnancy and risk for oral clefts: a meta-analysis

(Cleft lip OR cleft palate OR oral cleft OR cleft) AND (folic acid OR Vitamin B9 OR B9 OR folate)

48

0

Birth Defects Res C Embryo Today

Genetic and nongenetic etiology of nonsyndromic anorectal malformations: a systematic review

(Anal atresia OR anorectal defect OR anorectal malformation OR birth defect) AND (genes OR genetic OR risk factors OR etiology)

2833

114

J Hum Lact

Immune markers in breast milk and fetal and maternal body fluids: a systematic review of perinatal concentrations

(Immune markers OR cytokine OR chemokine OR immunoglobulin) AND (breast milk OR amniotic fluid OR maternal serum OR cord serum OR saliva OR mucus)

424

2

J Midwifery Womens Health

Improving quality and safety in maternity care: the contribution of midwife-led care

(humanized care OR midwife OR physiologic birth OR home birth) AND (safety OR quality OR efficacy OR outcome)

1555

0

Arch Dis Child Fetal Neonatal Ed

Interleukin-6 (−174C) polymorphism and the risk of sepsis in very low birth weight infants: meta-analysis

(Infant, Newborn OR Infant, Premature OR Infant, Low Birth Weight) AND (cytokines OR interleukin-6 OR IL-6 OR genetics)

1183

0

BMC Pregnancy Childbirth

Key components of early intervention programs for preterm infants and their parents: a systematic review and meta-analysis

(Preterm infants OR preterm OR very low birthweight OR low birthweight OR premature) AND (intervention OR early intervention OR program OR guideline)

2661

3

Birth Defects Res A Clin Mol Teratol

Major, non-chromosomal, birth defects and maternal physical activity: a systematic review

(Physical activity OR exercise OR activity OR maternal exercise OR maternal physical activity) AND (birth defects OR defect)

2839

19

Matern Child Health J

Maternal mortality among migrants in western Europe: a meta-analysis

(Ethnic OR ethnic group OR migrant OR immigrant OR minority OR disparity OR ‘‘foreign nationality’’ OR ‘‘foreign nationals’’) AND (‘‘maternal mortality’’ OR ‘‘pregnancy-related mortality’’ OR ‘‘pregnancy-related death’’ OR ‘‘maternal deaths’’ OR maternal health)

66

1

Arch Dis Child Fetal Neonatal Ed

Music for medical indications in the neonatal period: a systematic review of randomised controlled trials

(Infant OR newborn OR neonate OR neonatal) AND (music OR music therapy)

25

0

Matern Child Health J

Nature or nurture: a systematic review of the effect of socio-economic status on the developmental and cognitive outcomes of children born preterm

((Preterm OR premature) AND (birth OR delivery OR infant)) OR (prematurity OR “low birth weight”) AND (social OR socioeconomic OR sociodemographic OR environment*) AND (intelligence OR “iQ” or cogniti* OR academic OR development)

2641

11

Arch Dis Child Fetal Neonatal Ed

Network meta-analysis of indomethacin versus ibuprofen versus placebo for PDA in preterm infants

(Infant OR newborn OR neonate OR neonatal) AND (ductus arteriosus OR Patent ductus OR PDA) AND (indomethacin OR ibuprofen OR cyclooxygenase inhibitors OR NSAID)

47

0

Arch Dis Child Fetal Neonatal Ed

Opioids for neonates receiving mechanical ventilation: a systematic review and meta-analysis

(Infant OR newborn OR neonate OR neonatal) AND (morphine OR diamorphine OR fentanyl OR alfentanil OR sufentanil OR pethidine OR meperidine OR codeine OR methadone OR narcotics) AND (mechanical ventilation OR ventilation OR respiration)

26

0

J Obstet Gynecol Neonatal Nurs

Parenting in the neonatal intensive care unit

(Parent OR parenting OR parents OR family OR family-centered care) AND (neonate OR neonatal intensive care unit OR NICU or intensive care OR ICU OR neonatal nursing)

644

0

Paediatr Perinat Epidemiol

Prenatal alcohol exposure and childhood balance: a systematic review

(Balance OR motor performance OR motor function OR coordination OR postural control OR posture) AND (child OR child development OR preschool child) AND (alcohol OR alcohol abuse) AND (maternal OR in utero OR pregnancy OR prenatal)

4

0

Midwifery

Psychosocial correlates of exclusive breastfeeding: a systematic review

(Breastfeeding OR breast feeding OR breast milk OR exclusive breastfeeding) AND (psychosocial OR duration OR predictors OR social OR support)

492

2

J Midwifery Womens Health

Results of microbial testing exploring the etiology of deep breast pain during lactation: a systematic review and meta-analysis of nonrandomized trials

(Breastfeeding OR lactation OR breast milk) AND (infection OR breast pain OR microbial OR mastitis OR nipple pain OR disease)

1262

4

Paediatr Perinat Epidemiol

Review of self-reported physical activity assessments for pregnancy: summary of the evidence for validity and reliability

(Physical activity OR exercise) AND (pregnancy OR gestation OR maternity) AND (questionnaire OR reliability OR validity OR review OR self-reported)

244

7

Paediatr Perinat Epidemiol

Systematic review and meta-analysis investigating breast feeding and childhood wheezing illness

(Breast-feeding OR milk, human OR infant formula OR bottle feeding) AND (asthma OR atopy OR atopic OR wheeze)

60

0

BMC Pregnancy Childbirth

Systematic review of clinical trials on dietary interventions to prevent excessive weight gain during pregnancy among normal weight, overweight and obese women

(Diet OR dietary intervention OR food intake OR eating habits) AND (gestational OR pregnancy) AND (weight OR weight gain)

314

2

Birth

Systematic review of the literature on postpartum care: effectiveness of interventions for smoking relapse prevention, cessation, and reduction in postpartum women

(Postpartum OR postpartum period OR neonate OR infant OR newborn) AND (smoking cessation OR maternal Smoking OR smoking)

127

0

Paediatr Perinat Epidemiol

Vitamin A and carotenoids during pregnancy and maternal, neonatal and infant health outcomes: a systematic review and meta-analysis

(Vitamin A OR carotenoids OR carotenoid) AND (pregnancy OR birth outcome OR infant OR growth OR mortality OR newborn OR neonate)

499

8