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Table 4 Chi squared test for the difference in OI prevalence by age at enrolment before and after HAART

From: Frequency and distribution patterns of opportunistic infections associated with HIV/AIDS in Uganda

 

Prevalence

p value

Age < 30 (n = 8070), n (%)

Age = 30–39 (n = 10,008), n (%)

Age ≥ 40 (n = 6223), n (%)

Before HAART (2001–2003)

 Opportunistic infection

  Geohelminths

2187 (27.1)

2536 (25.3)

1714 (27.5)

0.058

  Diarrhoea

2422 (30.0)

3117 (31.1)

1907 (30.6)

0.671

  Oral candida

2586 (32.0)

3625 (36.2)

2213 (35.6)

<0.001

  Mycobacterium tuberculosis

1350 (16.7)

1706 (17.0)

1251 (20.1)

0.031

  Bacterial pneumonia

905 (11.2)

1113 (11.1)

706 (11.3)

0.139

  Genital ulcer

667 (8.3)

802 (8.0)

390 (6.3)

0.026

  Confirmed malaria

1277 (15.8)

1518 (15.2)

863 (13.9)

0.029

  Esoph candida

654 (8.1)

945 (9.4)

585 (9.4)

0.126

  Herpes zoster

505 (6.3)

568 (5.7)

351 (5.6)

0.198

  Cryptosporidiosis

269 (1.6)

387 (1.7)

238 (1.6)

0.218

  Cryptococcosis

133 (1.6)

182 (1.8

110 (1.8)

0.707

  Others

130 (3.3)

175 (3.9)

99 (3.8)

0.168

 Opportunistic cancer

  Kaposi’s sarcoma/HHV8

57 (0.7)

104 (1.0)

48 (0.8)

0.052

 

Prevalence

p value

Age < 30 (n = 17,872), n (%)

Age = 30-39 (n = 23,395), n (%)

Age ≥ 40 (n = 16,935), n (%)

Early HAART (2004–2008)

 Opportunistic infection

  Geohelminths

5849 (32.7)

7690 (32.9)

5645 (33.3)

0.365

  Diarrhoea

4323 (24.2)

6034 (25.8)

4555 (26.9)

0.010

  Oral candida

2919 (16.3)

4510 (19.3)

3191 (18.8)

<0.0001

  Mycobacterium tuberculosis

3073 (17.2)

4366 (18.7)

3150 (18.6)

0.006

  Bacterial pneumonia

1277 (7.1)

1930 (8.2)

1331 (7.9)

0.009

  Genital ulcer

1850 (10.4)

2634 (11.3)

1609 (9.5)

<0.0001

  Confirmed malaria

1230 (6.9)

1366 (5.8)

883 (5.2)

<0.0001

  Esoph candida

1342 (7.5)

2309 (9.9)

1648 (9.7)

<0.0001

  Herpes zoster

1080 (6.0)

1554 (6.6)

1106 (6.5)

0.407

  Cryptosporidiosis

554 (2.6)

823 (3.0)

649 (3.6)

0.039

  Cryptococcosis

236 (1.3)

399 (1.7)

286 (1.7)

0.011

  Others

464 (3.1)

712 (3.5)

608 (3.8)

0.07

 Opportunistic cancer

  Kaposi’s sarcoma/HHV8

166 (0.9)

290 (1.2)

221 (1.3)

0.009

 

Prevalence

p value

Age < 30 (n = 21,479), n (%)

Age = 30-39 (n = 23,168), n (%)

Age ≥ 40 (n = 17,174), n (%)

Late HAART (2009–2013)

 Opportunistic infection

  Geohelminths

5230 (24.3)

5489 (23.7)

4119 (24.0)

0.598

  Diarrhoea

3153 (14.7)

3352 (14.5)

2372 (13.8)

0.025

  Oral candida

1442 (6.7)

1748 (7.5)

1305 (7.6)

0.015

  Mycobacterium tuberculosis

1194 (5.6)

1423 (6.1)

911 (5.3)

0.008

  Bacterial pneumonia

1481 (6.9)

1601 (6.9)

1218 (7.1)

0.673

  Genital ulcer

1454 (6.8)

1479 (6.4)

827 (4.8)

<0.0001

  Confirmed malaria

934 (4.3)

896 (3.9)

524 (3.1)

<0.0001

  Esoph candida

595 (2.8)

662 (2.9)

492 (2.9)

0.958

  Herpes zoster

775 (3.6)

856 (3.7)

670 (3.9)

0.069

  Cryptosporidiosis

228 (1.7)

259 (1.7)

204 (2.2)

0.027

  Cryptococcosis

113 (0.5)

178 (0.8)

124 (0.7)

0.010

  Others

362 (1.1

405 (1.1)

374 (1.2)

0.973

 Opportunistic cancer

  Kaposi’s sarcoma/HHV8

86 (0.4)

132 (0.6)

91 (0.5)

0.055

  1. HHV8 human herpes virus 8, n number of patients