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Table 2 Predictors of incidence of HSV-2

From: Prevalence of Herpes Simplex Virus 2 (HSV-2) infection and associated risk factors in a cohort of HIV negative women in Durban, South Africa

Variable

Univariate analysis

Multivariate analysis

Hazard ratio (95% CI)

p value

Hazard ratio (95% CI)

p value

Age*

 <23

1

 

1

 

 23–27

1.18 (0.91–1.54)

0.213

1.21 (0.93–1.58)

0.155

 28–37

1.20 (0.93–1.55)

0.157

1.27 (0.98–1.64)

0.066

 38+

1.57 (1.23–2.00)

<0.001

1.71 (1.34–2.19)

<0.001

Employed/income

 Yes

1.03 (0.88–1.30)

0.805

  

 No

1

   

Religion

 Other

1

   

 Christian

1.21 (1.01–1.44)

0.040

–

–

Education

 ≥High school

1

   

 <High school

1.11 (0.91–1.35)

0.289

  

Age at first sex act (years)

 >15 

1

   

 <15

1.11 (0.76–1.64)

0.586

–

–

STI

 C. trachomatis

1.07 (0.80–1.43)

0.663

–

–

 N. gonorrhea

0.76 (0.49–1.18)

0.221

–

–

 Syphilis

1.23 (0.66–2.31)

0.510

–

–

 T. vaginalis

0.97 (0.71–1.32)

0.835

–

–

Contraception

 None

1

   

 Othera

1.39 (1.08–1.82))

0.012

–

–

 Hormonal

0.86 (0.59–1.25)

0.416

–

–

 Condom

0.93 (0.75–1.14)

0.481

–

–

Biological factors

 STI (s) baseline

1.04 (0.84–1.29)

0.705

–

–

 STI (s) incidence

1.13 (0.90–1.42)

0.314

–

–

 HIV incidence

1.71 (1.30–2.24)

<0.001

1.84 (1.40–2.42)

<0.001

 Pregnancy incidence

1.25 (0.93–1.67)

0.133

1.37 (1.02–1.83)

0.038

  1. CI confidence interval
  2. aIncludes tubal ligation, intrauterine devices and traditional methods
  3. * Median (IQR) = 27 (23–37); p value for rank test was <0.001
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BMC Research Notes

ISSN: 1756-0500

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