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Table 1 Changes in mPAP, PWP and PVR from baseline to pulmonary hypertension

From: A pig model of acute right ventricular afterload increase by hypoxic pulmonary vasoconstriction

Pig

Baseline (BL)

Pulmonary hypertension (PH)

FiO2

mPAP

(mmHg)

PWP

(mmHg)

CO

(l/min)

PVR

(dyn s/cm5)

FiO2

mPAP

(mmHg)

PWP

(mmHg)

CO

(l/min)

PVR

(dyn s/cm5)

1

0.30

22

11

3.5

251.4

0.15

34

11

3.9

471.8

2

0.30

17

7

3.2

250.0

0.21

31

7

4.0

480.0

3

0.30

17

7

2.4

333.3

0.13

25

7

3.0

480.0

4

0.30

14

7

2.2

254.5

0.13

25

5

3.9

410.3

5

0.30

17

7

4.5

177.8

0.14

26

8

4.5

320.0

6

0.30

15

8

3.4

164.7

0.14

25

8

2.9

469.0

7

0.30

27

6

4.3

390.7

0.15

36

6

2.5

960.0

8

0.30

17

9

3.0

213.3

0.15

25

9

2.9

441.4

  1. Both mPAP and PVR increase with reduction of FiO2 and globally induced hypoxic pulmonary vasoconstriction
  2. FiO 2 fraction of inspired oxygen, mPAP mean pulmonary arterial pressure, PWP pulmonary wedged pressure, CO cardiac output, PVR pulmonary vascular resistance