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Fig. 2 | BMC Research Notes

Fig. 2

From: Close contact interferon-gamma response to the new PstS1(285–374):CPF10: a preliminary 1-year follow-up study

Fig. 2

Mean, standard deviation (SD) of interferon-gamma responses at enrollment (T0) and after follow up (T1). Longitudinal analysis via Wilcoxon signed rank test of mean interferon-gamma levels after short- (WBA) and/or long-term (LSA) stimulation assays priming blood cells from recent close contacts with mycobacterial antigens [ESAT6:CFP10, PstS1/CFP10, and PstS1(285–374):CFP10] upon enrollment (T0) and after one-year follow up (T1). In some special cases, a blood specimen was collected upon TST conversion or an active TB diagnosis. All individuals in the study were stratified according to their initial (T0) tuberculin skin test (TST) response and T1 outcome, as follows: a Group I TSTneg (n, WBA = 10, LSA = 17); b Group II TST convertors (n, WBA = 2, LSA = 4); c Group III TSTpos treated for latent tuberculosis infection (tLTBI) (n, WBA = 17, LSA = 25); d Group IV TSTpos not treated for tLTBI (n, WBA = 4, LSA = 5); and e Group V TB incident cases (n = 2). Short bars standard deviation

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