Fig. 1

CCRs found in case 1 and 2 and flow cytometric analyses of NK cell subsets. Case 1: a CCR—der(1)t(1;4),der(4)t(1;4;?),ace(1),ace(1). b, flow cytometric analyses of NK cell of case 1. Show all NK cells (CD56 positive) are CD16 negative, thus all are sub-sets of NK^bright. Case 2: c CCR- ins(2;4). Chromosome 2 was folded and thus looks shorter due to preparation. d flow cytometric analyses of NK cell of case 1. Show all NK cells (CD56 positive) are CD16 negative, thus all are sub-sets of NK^bright. a, b the probes were conjugated with TexasRed to label chromosome 1 (red), Diethylaminocoumarin (DEAC) for chromosome 2 (lightblue) and fluorescein isothiocyanate (FITC) for chromosome 4 (green). Other chromosomes were counterstained with DAPI (dark blue). c, d BD FACSCanto II cytometer was used in both cases and the data analyses were performed using the Infinicyt^® software