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Fig. 6 | BMC Research Notes

Fig. 6

From: A computational protocol to evaluate the effects of protein mutants in the kinase gatekeeper position on the binding of ATP substrate analogues

Fig. 6

Comparison of the catalytic efficiency and predicted interaction energy for v-Src, v-SrcI338A, and v-SrcI338G with ATP (a) and with N6-(benzyl) ATP (b). Plots show the trend of the kcat/Km ratio and the predicted interaction. Shown on the x-axis are the wild-type protein and the two mutants. The primary y-axis (on the left) is the predicted negative interaction energies and the secondary y-axis (on the right) is the log of the kcat/Km ratio

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BMC Research Notes

ISSN: 1756-0500

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