The discovery of novel LPMO families with a new Hidden Markov model

BMC Research Notes

Table 1 Overview of characterized AA9, AA10, AA11 and AA13 enzymes used to build the Hidden Markov model

Organism	Uniprot ID	PDB ID	Substrate	Cleavage site	Auxiliary activity family	References
Neurospora crassa OR74A	Q1K8B6	4EIR	Cellulose	C4	AA9 (formerly GH61)	[11,12,13]
Neurospora crassa OR74A	Q7SA19	4EIS	Cellulose	C1, C4	AA9 (formerly GH61)	[11, 12]
Phanerochaete chrysosporium K-3	H1AE14	4B5Q	Cellulose	C1	AA9 (formerly GH61)	[14, 15]
Thermoascus aurantiacus	G3XAP7	2YET	Cellulose	C1	AA9 (formerly GH61)	[16]
Enterococcus faecalis V583	Q838S1	4A02	Chitin	C1	AA10 (formerly CBM33)	[4, 17]
Burkholderia pseudomallei 1710b	Q3JY22	3UAM	n.d.	n.d.	AA10 (formerly CBM33)	[18]
Vibrio cholerae O1 biovar El Tor str. N16961	Q9KLD5	2XWX	n.d.	n.d.	AA10 (formerly CBM33)	[19]
Bacillus amyloliquefaciens DSM7	E1UUV3	2YOX	n.d.	n.d.	AA10 (formerly CBM33)	[20]
Serratia marcescens BJL200	O83009	2BEM	Chitin	C1	AA10 (formerly CBM33)	[4,5,6]
Streptomyces coelicolor A3(2)	Q9RJC1	4OY6	Cellulose, chitin	C1, C4	AA10 (formerly CBM33)	[7]
Streptomyces coelicolor A3(2)	Q9RJY2	4OY7	Cellulose	C1, C4	AA10 (formerly CBM33)	[6,7,8]
Thermobifida fusca YX	Q47QG3	4GBO	Cellulose, chitin	C1, C4	AA10 (formerly CBM33)	[7]
Aspergillus oryzae RIB40	Q2UA85	4MAI	chitin	C1	AA11	[9]
Aspergillus oryzae RIB40	Q2U8Y3	4OPB	n.d.	n.d.	AA13	[10]

ISSN: 1756-0500