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Table 1 Published cases of prostaglandin analogue related cystoid macular edema after uncomplicated cataract surgery in eyes without other risk factors

From: Cystoid macular edema associated with preservative-free latanoprost after uncomplicated cataract surgery: case report and review of the literature

Study PGA Time from cataract surgery and CME diagnosis Duration of PGAs treatment Outcome Action taken Additional information
Costagliola et al. [5] LP 2 years 5 days Complete resolution of CME within days LP discontinuation and treatment with diclofenac  
Altintas et al. [6] LP 10 days 3 years Complete resolution of CME in 3 months Discontinuation of LP and initiation of topical and oral acetazolamide Pseudoexfoliative glaucoma
LP not discontinued perioperatively
LP 1 month 2 months CME resolved in 4 months Initiation of ketorolac eye drops and oral acetazolamide LP was discontinued 1 day preoperatively and was never re-administered
Extracapsular extraction
Dhingra et al. [7] LP 3 months Unknown CME resolved LP discontinuation and sub-Tenon’s triamcinolone injection Only clinical diagnosis
LP not discontinued perioperatively
Ozdemir et al. [8] LP 2 years 1 month CME resolution in 3 weeks LP discontinuation Extracapsular cataract extraction
Serous retinal detachment
Agange et al. [9] LP 4 months Years CME resolved LP discontinuation and treatment with diclofenac Advanced pigmentary glaucoma
CME recurred twice after PGA administration LP was resumed immediately postoperatively
Panteleontidis et al. [10] LP 3 months 4 years Complete resolution of CME 1 month later Recurrence of CME after LP administration Discontinuation of LP Pseudoexfoliative glaucoma
No statement of LP discontinuation perioperatively
LP 3 weeks 7 years Complete resolution of CME 3 weeks later LP discontinuation and treatment with ketorolac Pseudoexfoliative glaucoma
No statement of LP discontinuation perioperatively
LP 1 month 2 years Complete resolution of CME 3 weeks later LP discontinuation and treatment with ketorolac Pseudoexfoliative glaucoma No statement of LP discontinuation perioperatively
Sacchi et al. [11] Tafluprost 2 months 1 year Refractory CME which resolved after an intravitreal implant of dexamethasone Tafluprost discontinuation Preservative free tafluprost
Treatment with topical nepafenac and oral indomethacin, sub-Tenon’s, dexamethasone intravitreal implant Serous retinal detachment
LP not discontinued perioperatively
  1. PGA Prostaglandin analogue, CME Cystoid macular edema, LP Latanoprost
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