Gene expression differences between PAXgene and Tempus blood RNA tubes are highly reproducible between independent samples and biobanks

Table 1 Contrasts produced from comparing expression profiles in PAXgene and Tempus tubes

Contrast	Experiment	Protocol	Sign. probes*	Sign. Transcripts*
c1	1	Original	3143	2883
c2	1	Modified	1540	1469
c3	2	Original	2236	2068
c4	2	Modified	1440	1346
c5	3	Modified	7142	6250

“Contrast” enumerates the five statistical comparisons specified by “Experiment” and “Protocol”; see Fig. 1. “Sign. probes” are the number of probes on the Illumina microarray (total probes: 47323) with significantly different signals in PAXgene compared with Tempus (* p < 0.05); “Sign. Transcripts” are the number of distinct transcripts targeted by the significant probes

ISSN: 1756-0500