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Table 2 Comparison of results between stability-based and FDR-adjusted methods for the spiked-in data set for four selection methods (true biomarkers in italics font)

From: Performance of variable selection methods using stability-based selection

Method Test statistic Biomarkers selected pAUCa, sensitivity 1-Specificity
Stability (0.5) VIP Gly Ser Thr Ala Val Lys 20 36 24 13 42 23 41 44 57 19 Asp 0.875 0.169
  Student t test Gly Ser Thr Ala Val Lys 20 36 13 23 42 41 Asp 44 57 24 48 0.875 0.169
  Lasso Gly Ala Val 20 23 Thr 21 0.5 0.034
  Elastic net Gly Ala Val 23 20 Thr 0.5 0.051
FDR Student t test P values <0.05 Gly Ser Thr Ala Val Lys 25 0.75 0.034
  VIP P values adj <0.05 0 0
  1. a pAUC Partial area under the receiver operating characteristic curve (0.2)