Table 2 Comparison of results between stability-based and FDR-adjusted methods for the spiked-in data set for four selection methods (true biomarkers in italics font)
From: Performance of variable selection methods using stability-based selection
Method | Test statistic | Biomarkers selected | pAUCa, sensitivity | 1-Specificity |
|---|---|---|---|---|
Stability (0.5) | VIP | Gly Ser Thr Ala Val Lys 20 36 24 13 42 23 41 44 57 19 Asp | 0.875 | 0.169 |
| Â | Student t test | Gly Ser Thr Ala Val Lys 20 36 13 23 42 41 Asp 44 57 24 48 | 0.875 | 0.169 |
| Â | Lasso | Gly Ala Val 20 23 Thr 21 | 0.5 | 0.034 |
| Â | Elastic net | Gly Ala Val 23 20 Thr | 0.5 | 0.051 |
FDR | Student t test P values <0.05 | Gly Ser Thr Ala Val Lys 25 | 0.75 | 0.034 |
|  | VIP P values adj <0.05 | – | 0 | 0 |