Iguchi et al. | Sewpaul et al. | Backman et al. | Wong et al. | Manfro et al. | |
---|---|---|---|---|---|
Patient gender/age (year) | Female/56 | Male/48 | Male/36 | Female/44 | Male/36 |
Allograft type | Living-related | Living-related | Living | Cadaveric | Cadaveric |
Biopsy time after transplant w/nephrocalcinosis | 10 days | 7 days | 3 days | 18 days (biopsy at 3 days showed acute cellular rejection w/o calcium crystals) | 15 days |
Other lesions | Borderline acute rejection | Acute tubular necrosis | None | Acute tubular necrosis | Acute tubular necrosis |
Serum calcium | Slightly increased | Markedly increased | Normal | Normal | Normal |
Serum phosphate | Slightly increased | Slightly increased | Normal | Markedly increased | Markedly increased |
Follow-up | Graft function improved after supportive treatment | Parathyroidectomy improved hypercalcemia and graft function | Parathyroidectomy improved graft function. Decreased amount of calcium crystals in follow-up biopsy | Graft loss within 5 months. Serial biopsy showed gradual increase in calcium crystals and tubulointerstitial fibrosis | Repeat biopsy at day 85 showed no calcification. Stable graft function at 1 year |