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Table 2 Resistance to first and second-line anti-tuberculous medication among MDR-TB patients at Jinnah Postgraduate Medical Center, Karachi, Pakistan (2009–2012)

From: Emergence of fluoroquinolone resistance among drug resistant tuberculosis patients at a tertiary care facility in Karachi, Pakistan

 

Number of cases with resistance

n

(%)

Any resistance (first line drugs)

 Isoniazid (H)

130

(97.7)

 Rifampicin (R)

129

(96.9)

 Pyrazinamide (Z)

115

(86.4)

 Ethambutol (E)

92

(69.2)

 Streptomycin (S)

86

(64.6)

Any resistance (second line drugs)

 Kanamycin (Km)

1

(0.8)

 Amikacin (Am)

2

(1.5)

 Capreomycin (Cm)

2

(1.5)

 Ofloxacin (Ofx)

49

(34.6)

 Ethionamide (Eto)

3

(2.3)

 Cycloserine (Cs)

1

(0.8)

Combined resistance of H with other drugs

 H + Z

114

(85.7)

 H + E

91

(68.4)

 H + S

86

(64.7)

 H + Z + E

90

(67.7)

 H + Z + E + S

67

(50.4)

 H + Ofx

45

(33.9)