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Table 2 Richness, alpha-diversity, and relative abundance of fecal microbiome in infants with bronchiolitis and healthy controls

From: Sphingolipid metabolism potential in fecal microbiome and bronchiolitis in infants: a case–control study

  Infants with bronchiolitis n = 40 Healthy control infants n = 115 P value
Richness, median (IQR)
 Number of genera 17 (13–23) 13 (10–18) 0.004
Alpha-diversity, median (IQR) shannon index 2.21 (1.68–2.65) 1.93 (1.44–2.49) 0.27
Relative abundance of 10 most abundant genera, mean (standard deviation)
 Escherichia 0.21 (0.24) 0.23 (0.26) 0.91*
 Bifidobacterium 0.16 (0.20) 0.20 (0.21) 0.49*
 Enterobacter 0.10 (0.21) 0.17 (0.24) 0.27*
 Bacteroides 0.20 (0.23) 0.10 (0.19) 0.10*
 Veillonella 0.03 (0.09) 0.06 (0.12) 0.31*
 Lachnospiraceae incertae sedis 0.06 (0.10) 0.04 (0.10) 0.49*
 Streptococcus 0.02 (0.09) 0.03 (0.05) 0.91*
 Clostridium sensu strictos 1 0.01 (0.01) 0.03 (0.06) 0.16*
 Enterococcus 0.01 (0.03) 0.02 (0.04) 0.48*
 Akkermansia 0.02 (0.09) 0.02 (0.08) 0.91*
Microbiome profile, n (%)    0.01
 Bacteroides-dominant profile 19 (48) 24 (21)  
 Bifidobacterium-dominant profile 6 (15) 26 (23)  
 Escherichia-dominant profile 10 (25) 36 (31)  
 Enterobacter/Veillonella-dominant profile 5 (12) 29 (25)  
  1. IQR interquartile range
  2. * Benjamini–Hochberg corrected false discovery rate (q value) accounting for multiple comparisons