Fig. 1
A Measurement of inhibition caused by treatment with IFN-γ on several pathogenic fungi using the XTT assay. The results were expressed as the percentage of the metabolic activity of treated cells compared to untreated cells. The absorbance reading at OD492 for the untreated control for each species was taken as 100%; the mean OD492 value was 0.44 (±0.07). The data shown are means and standard errors of the growth inhibition (treated/untreated control) from three replicate experiments. Data were analysed by t-test to compare low to high doses of IFN-γ (*p < 0.05, **p < 0.01, ***p < 0.001), p-values for each test are shown in the figure. B Measurement of inhibition caused by incubation of several pathogenic fungi with IFN-γ using the XTT assay over an extended dose range. No significant differences in fungal survival were found when treatment with 32 pg/ml to treatment with 50 or 100 pg/ml of IFN-γ were compared. Data in 1B were analysed by one-way ANOVA (p-value shown in the figure) and Dunn’s post-test (p-values shown as asterisks) to compare the range of doses of IFN-γ (*p < 0.05, **p < 0.01, ***p < 0.001). Asterisks indicate that doses are significantly different to the lowest dose