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Table 1 MCNS patient characteristics at sampling

From: Changes in DNA methylation in naïve T helper cells regulate the pathophysiological state in minimal-change nephrotic syndrome

Pt. no.

Sex

Age at onset

Total follow-up perioda, months

Total relapse timea

FR

Biopsy

Sampling age at rel

Relapse times at sampling

Intervalsb, weeks

PSL at relc mg/day

PLS at remc mg/d

IS at relc mg/day

IS at remc mg/day

CD14+, n = 6

RO−, n = 4

1

M

10 years, 4 months

96

6

Yes

MC

13 years, 0 months

3rd

5

40

10

0

0

Taken

Taken

2

M

5 years, 4 months

53

6

Yes

MC

6 years, 0 months

3rd

16

0

35

0

CyA90

Taken

Taken

3

M

5 years, 11 months

204

11

Yes

MC

18 years, 6 months

9th

23

10

15

0

0

Taken

Taken

4

M

7 years, 3 months

192

15

Yes

MC

19 years, 10 months

13th

23

60

5

0

0

Taken

Taken

5

M

9 years, 9 months

109

4

Yes

ND

11 years, 7 months

4th

12

0

0

CyA180

CyA160

Taken

NT

6

M

11 years, 11 months

79

8

Yes

ND

12 years, 5 months

4th

71

0

20

MZV125

MZV 75

Taken

NT

Mean

 

8 years, 4 months

122.2

8.3

  

13 years, 5 months

6th

25

      
  1. Patients for DNA methylation analysis
  2. FR frequent relapser, MC minimal change, ND not done, Rel relapse, Rem remission, PSL prednisolone, IS immunosuppressant, CyA cyclosporin A, MZB mizoribine, NT not taken
  3. aFollow-up period until December 2012
  4. bIntervals of sampling between relapse and remission
  5. cTreatment at the time of sampling