Skip to main content

Advertisement

Table 1 MCNS patient characteristics at sampling

From: Changes in DNA methylation in naïve T helper cells regulate the pathophysiological state in minimal-change nephrotic syndrome

Pt. no. Sex Age at onset Total follow-up perioda, months Total relapse timea FR Biopsy Sampling age at rel Relapse times at sampling Intervalsb, weeks PSL at relc mg/day PLS at remc mg/d IS at relc mg/day IS at remc mg/day CD14+, n = 6 RO−, n = 4
1 M 10 years, 4 months 96 6 Yes MC 13 years, 0 months 3rd 5 40 10 0 0 Taken Taken
2 M 5 years, 4 months 53 6 Yes MC 6 years, 0 months 3rd 16 0 35 0 CyA90 Taken Taken
3 M 5 years, 11 months 204 11 Yes MC 18 years, 6 months 9th 23 10 15 0 0 Taken Taken
4 M 7 years, 3 months 192 15 Yes MC 19 years, 10 months 13th 23 60 5 0 0 Taken Taken
5 M 9 years, 9 months 109 4 Yes ND 11 years, 7 months 4th 12 0 0 CyA180 CyA160 Taken NT
6 M 11 years, 11 months 79 8 Yes ND 12 years, 5 months 4th 71 0 20 MZV125 MZV 75 Taken NT
Mean   8 years, 4 months 122.2 8.3    13 years, 5 months 6th 25       
  1. Patients for DNA methylation analysis
  2. FR frequent relapser, MC minimal change, ND not done, Rel relapse, Rem remission, PSL prednisolone, IS immunosuppressant, CyA cyclosporin A, MZB mizoribine, NT not taken
  3. aFollow-up period until December 2012
  4. bIntervals of sampling between relapse and remission
  5. cTreatment at the time of sampling