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Table 4 Ingenuity pathway analysis of the 85 co-occurring genes

From: Changes in DNA methylation in naïve T helper cells regulate the pathophysiological state in minimal-change nephrotic syndrome

(a) Top molecules
Genes Description Chromosome Exp. value
SAC3D1 SAC3 domain containing 1 11q13.1 0.772
EIF3B Eukaryotic translation initiation factor 3, subunit B 7p22.3 0.692
PDF Peptide deformylase (mitochondrial) 16q22.1 0.680
FKBP1A FK506 binding protein 1A, 12 kDa 20p13 0.661
TIMP2 TIMP metallopeptidase inhibitor 2 17q25 0.586
RYR3 Ryanodine receptor 3 15q14-q15 0.567
U2AF2 U2 small nuclear RNA auxillary factor 2 19q13.42 0.558
B3GALT6 UDP-Gal:betaGal beta 1, 3-galactosyltransferase polypeptide 6 1p36.33 0.543
CBX7 Chromobox homolog 7 22q13.1 0.536
CDX19 Cyclin-dependent kinase 19 6q21 0.523
(b) Top canonical pathways
Name P value Ratio
Insulin receptor signaling 3.45E−03 3/139 (0.022)
Protein kinase A signaling 5.74E−03 4/327 (0.012)
Clarin-mediated endocytosis signalling 6.29E−03 3/172 (0/017)
Spliceosomal cycle 7.06E−03 1/10 (0.100)
Calcium signaling 7.93E−03 3/207 (0.014)