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Table 1 Selected characteristics of study sample

From: Associations of two-pore domain potassium channels and triple negative breast cancer subtype in The Cancer Genome Atlas: systematic evaluation of gene expression and methylation

Characteristic

Gene expressiona

Methylationb

N

[%]

N

[%]

Total

959

[100]

767

[100]

Race

 nH white

592

[85.6]

471

[78.6]

 nH black

100

[14.5]

128

[21.4]

Age (years)

 >/=50

682

[73.3]

477

[71.3]

 <50

248

[26.7]

192

[28.7]

Menopausal status

 Post

653

[76.1]

497

[75]

 Pre

205

[23.9]

165

[25]

Stage

 I

160

[17.3]

126

[17.4]

 II

536

[58]

402

[55.4]

 III

213

[23.1]

188

[25.9]

 IV

15

[1.6]

10

[1.4]

HR expression

 ER+/PR+

585

[65.6]

452

[65.8]

 ER+/PR−

104

[11.7]

78

[11.4]

 ER−/PR+

14

[3.3]

15

[2.2]

 ER−/PR−

189

[21.2]

142

[20.7]

Intrinsic subtype

 Luminal A

219

[45]

108

[51.4]

 Luminal B

116

[23.9]

43

[20.5]

 HER2+/HR−

55

[11.3]

14

[6.7]

 Basal-like

88

[18.1]

40

[19]

 Normal-like

8

[1.7]

5

[2.4]

Combined TN status endpoint

 Luminal A

472

[74.8]

398

[76.7]

 Triple negative

159

[25.2]

121

[23.3]

  1. nH non-Hispanic, HR hormone receptor, ER/PR estrogen and progesterone receptor, HER2 human epidermal growth factor receptor-2
  2. To demonstrate the basic distribution of study covariates:
  3. aAn expression ‘flag’ marker (KCNK2) with no missing values is used (mRNA Expression z-scores, RNA Seq V2 RSEM)
  4. bA methylation ‘flag’ marker (cg21415530, KCNK9) with no missing values is used