Effects of bacitracin methylene disalicylate and diet change on gastrointestinal integrity and endotoxin permeability in the duodenum of broiler chicken

Table 2 Changes in body weight, gastrointestinal integrity, and endotoxin permeability over time

	Unit	N	LSMean	SEM	P value
Body weight					<0.001
Day 0^a,b	Kg	8	1.59^x	0.04
Day 3	Kg	16	2.10^y	0.04
Day 7	Kg	16	2.53^z	0.04
Gastrointestinal integrity					<0.001
Day 0	Ω/cm²	8	396.3^z	14.3
Day 3	Ω/cm²	14^c	537.5^y	14.1
Day 7	Ω/cm²	14^c	519.4^y	13.6
Endotoxin permeability					0.903
Day 0	µg/ml/min/cm²	8	3395	2016
Day 3	µg/ml/min/cm²	16	5066	1886
Day 7	µg/ml/min/cm²	16	5808	1615

^a Day 0 (31 days post hatch) samples were taken as baseline samples prior to the switch in feed to a grower diet on day 0 that either contained 50 g/ton of bacitracin methylene disalicylate (BMD) or no BMD. Day 3 samples were taken 3 and 4 days following the feed change and occurred at 34 and 35 days post hatch, respectively. Day 7 samples were taken 7 and 8 days following the feed change and occurred at 38 and 39 days post hatch, respectively
^b Data were similar for BMD dietary treatment and the interaction of day and BMD treatment; therefore, data shown are for differences in day regardless of dietary treatment
^c Due to malfunctions with the chambers data was only collected on 7 broilers per treatment with a total of 14 measurements collected for each time point
^xyz changes in superscript within row indicate differences between pairwise comparisons after Tukey’s post hoc adjustment (P < 0.05)

ISSN: 1756-0500