Evaluation of Xpert MTB/RIF testing for rapid diagnosis of childhood pulmonary tuberculosis in children by Xpert MTB/RIF testing of stool samples in a low resource setting

Table 2 Performance characteristics of Xpert in stool in comparison with culture and gastric aspirate Xpert standards

Test	Reference standard	Number of patients included in evaluation	Sensitivity % (95% CI)	Specificity % (95% CI)	PPA (%)	NPA (%)	Kappa agreement (95% CI)
Stool Xpert	GA culture	49	88.9 (50.7–99.4)	95 (81.8–99.1)	88.9	95	0.804 (0.592–1.00)
GA Xpert	GA culture	49	100 (62.9–100)	95 (81.8–99.1)	100	95	0.875 (0.706–1.00)
GA Xpert	Stool Xpert	49	81.8 (47.8–96.8)	97.4 (84.6–99.9)	81.8	97.3	0.818 (0.62–1.00)

Sensitivity, specificity, 95% confidence intervals (CI), positive percent agreement (PPA), and negative percent agreement (NPA), and kappa scores were calculated in MS Excel

ISSN: 1756-0500