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Table 2 Performance characteristics of Xpert in stool in comparison with culture and gastric aspirate Xpert standards

From: Evaluation of Xpert MTB/RIF testing for rapid diagnosis of childhood pulmonary tuberculosis in children by Xpert MTB/RIF testing of stool samples in a low resource setting

Test Reference standard Number of patients included in evaluation Sensitivity % (95% CI) Specificity % (95% CI) PPA (%) NPA (%) Kappa agreement (95% CI)
Stool Xpert GA culture 49 88.9 (50.7–99.4) 95 (81.8–99.1) 88.9 95 0.804 (0.592–1.00)
GA Xpert 49 100 (62.9–100) 95 (81.8–99.1) 100 95 0.875 (0.706–1.00)
GA Xpert Stool Xpert 49 81.8 (47.8–96.8) 97.4 (84.6–99.9) 81.8 97.3 0.818 (0.62–1.00)
  1. Sensitivity, specificity, 95% confidence intervals (CI), positive percent agreement (PPA), and negative percent agreement (NPA), and kappa scores were calculated in MS Excel