Table 3 Response to treatment (change in depressive symptoms) LWWS 2
Variable | Control | Confidence interval | Combined intervention | Confidence interval | F | p (combined intervention vs control)* |
|---|---|---|---|---|---|---|
Depressive symptoms (HDRS) percent change over time—primary endpoints shaded | ||||||
HDRS % change 8 weeks (mean, SD) | (N = 26) − 33.2 (22.5) | − 42.3 to − 24.1 | (N = 65) − 39.3 (26.4) | − 45.8 to − 32.7 | 1.07 | 0.304 |
HDRS % change 21 weeks (mean, SD) | (N = 25) − 38.5 (28.3) | − 50.2 to − 26.9 | (N = 63) − 40.1 (29.5) | − 47.6 to − 32.7 | 0.05 | 0.82 |
HDRS % change 12 months (mean, SD) | (N = 25) − 39.0 (25.1) | − 49.4 to − 28.7 | (N = 63) − 42.1 (31.9) | − 50.1 to − 34.1 | 0.19 | 0.67 |
Time point | Control (N, %) | Combined intervention (N, %) | Odds ratio | Confidence interval | p combined intervention vs control** |
|---|---|---|---|---|---|
Remission (HDRS ≤ 9) over time LWWS2—primary endpoints shaded | |||||
8 weeks (T2) N = 91 | 7/26 (27%) | 24/65 (37%) | 1.6 | 0.58 to 4.33 | 0.36 |
21 weeks (T3) N = 88 | 9/25 (36%) | 25/63 (40%) | 0.6 | 0.45 to 3.1 | 0.75 |
12 months (T4) N = 88 | 9/25 (36%) | 28/63 (44%) | 0.7 | 0.55 to 3.7 | 0.47 |