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Table 3 Results of multivariate logistic regression analysis for factors associated with timely titration of ACEI among heart failure patients at the cardiac clinic of Ayder Comprehensive Specialized Hospital, 2016

From: Treatment optimization of angiotensin converting enzyme inhibitors and associated factors in Ayder Comprehensive Specialized Hospital: a cross-sectional study

Variable

Timely titration

COR, 95% CI

p value

AOR, 95% CI

p value

No, n (%)

Yes, n (%)

Duration of heart failure diagnosis (year)

 ≤ 1

25 (80.6)

6 (19.4)

1.00

 

1.00

 

 > 1

29 (96.7)

1 (3.3)

0.144 (0.02–1.78)*

0.082

0.102 (0.01–1.22)*

0.071

Type(s) of combination medications

 ACEI and beta-blockers

28 (93.3)

2 (6.7)

1.00

 

1.00

 

 ACEI and CCB

2 (50.0)

2 (50.0)

14.00 (1.23–158.84)**

0.033

21.68 (1.23–383.16)**

0.036

 ACEI and diuretics

19 (90.5)

2 (9.5)

1.47 (0.19–11.39)

0.710

1.25 (0.15–10.22)

0.835

 Any other combinationsa

54 (88.5)

7 (11.5)

2.80 (0.212–37.03)

0.434

2.86 (0.19–43.34)

0.447

  1. AOR, Adjusted odds ratio; CCB, calcium channel blockers; CI, Confidence interval; COR, Crude odds ratio
  2. * Statistically significant at p < 0.1
  3. ** Statistically significant at p < 0.05
  4. aAny other combinations: ACEI and statins, ACEI and anticoagulants, ACEI and digoxin