Fig. 1
From: Using DIVAN to assess disease/trait-associated single nucleotide variants in genome-wide scale
a Illustration of using DIVAN to obtain D-scores of known variants by variant identifiers. The input file contains a list of variant identifiers with each variant as one row. The output file contains tab-delimited columns representing variant identifier, D-score, chromosome, chromosome position and D-score percentile of each variant respectively. b Illustration of using DIVAN to obtain D-scores of known variants fall inside genomic regions of interest. The input file contains a list of genomic regions in the format of tab-delimited chromosome, start and end positions. The D-scores of known variants located within each genomic region are reported. The output file contains tab-delimited columns representing chromosome, start and end positions, variant identifier, position of variant and D-score with its corresponding percentile of each variant respectively. c Illustration of using DIVAN to obtain average D-scores of genomic regions of interest. The input file contains a list of genomic regions in the format of tab-delimited chromosome, start and end position. The mean and standard deviation of D-scores for all bases within each genomic region are calculated. The output file contains tab-delimited columns representing chromosome, start and end positions, mean of D-scores with the corresponding percentile and standard deviation of D-scores for each region respectively