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Table 1 Patient’s baseline characteristics

From: Relationship between Trypanosoma brucei rhodesiense genetic diversity and clinical spectrum among sleeping sickness patients in Uganda

Characteristic Early stage Late stage P value
Disease stage 6 18 (75%) < 0.001*
Sex (male/female) 5/1 11/7 0.319
Age (median) 17.8 24.5 0.444
Trypanosomes in CSF 0 16 (66.7%) < 0.00*
Parasitemia/ml 19.2 × 104 36.1 × 104 0.399
CSF parasitosis/ml 0 8.0 × 104 < 0.01*
Disease duration (median) 0.5 1.3 0.173
Clinical presentation
 Fever 6 17 (100%) 1.0
 Headache 6 16 (94.1%) 0.417
 Hepatomegaly 0 2 (8.7%) 0.538
 Lymphadenopathy 2 6 (26.1%) 0.666
 Splenomegaly 0 6 (26.1%) 0.123
 Edema 0 4 (17.4%) 0.232
 Somnolence 1 8 (34.8%) 0.208
 Gait abnormalities 0 6 (26.1%) 0.123
 Tremors 0 2 (8.7%) 0.538
 Urinary incontinence 0 2 (8.7%) 0.538
 Cranioneuropathy 0 2 (9.1%) 0.519
 Reactive encephalopathy 0 1 (4.3%) 0.739
Glasgow coma score
 Mild (13–150) 6 12 (54.5%) 0.217
 Moderate (9–12) 0 3  
 Severe (≤ 8) 0 1  
  1. * Significantly higher in late stage patients