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Table 1 Summary of the clinical characteristics of the donor liver studied

From: Subunit composition of respiratory chain complex 1 and its responses to oxygen in mitochondria from human donor livers

 

Liver 1

Liver 2

Liver 3

Liver 4

Liver 5

Donor age (years)

47

60

49

55

59

Graft type

DBD

DCD

DCD

DCD

DBD

Steatosis

50%

0%

30%

20%

0%

WIT (min)

NA

24

15

20

NA

CIT (h)

8

12

12

10

10

Reason for clinical discard

Steatohepatitis with fibrosis

Perfusion concern

Steatosis

Lymphoproliferative disorder

Cholangiocarcinoma concern

  1. Graft types studied included donor after brain stem death (DBD) and donor after cardiac death (DCD). Liver steatosis is expressed as a percentage (%) based on histological assessment of the liver using Hematoxylin and Eosin stain. The warm ischemic time (WIT) is only applicable to the DCD liver and is from the time of oxygen saturation of 70% or systolic blood pressure of 50 mmHg in the donor to the time of aortic cannulation in the donor. The cold ischemic time (CIT) for this study is from the time of aortic cannulation in the donor to the time when anterograde persufflation (O2 exposure) starts. NA Not applicable