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Table 2 Single nucleotide polymorphisms (SNPs) of G478

From: PVL overexpression due to genomic rearrangements and mutations in the S. aureus reference strain ATCC25923

SNP

G477 position

G478 position

Locus

Gene

Function

NA change (G477 to G478)

AA change (G477 to G478)

1

464,504

464,504

Intergenic

Between recR and rrs, polyT

(Sequencing error?)

G to T

None

2

705,579

705,579

CDS

yflS

Putative malate transporter

T to A

None (silent mutation)

3

768,873

768,873

CDS

degV1

Putative fatty-acid-binding protein

G to C

AA 179: A to P

4

1,318,286

1,318,286

CDS

thrB

Homoserine kinase

T to C

AA 153: M to T

5

1,333,827

1,333,827

CDS

sbcC

Nuclease Sbc subunit C

C to T

None (silent mutation)

6

2,051,482

2,051,482

Intergenic

Between AIO21657 and AIO21658

Mobile element

G to A

None

7

2,174,003

2,187,357

CDS

Q5HE59

Putative RNA binding protein

G to A

AA 454: T to V

8

2,174,004

2,187,358

CDS

Q5HE59

Putative RNA binding protein

T to C

AA 454: T to V (see above)

9

2,373,530

2,386,884

CDS

fni

Isopentenyl-diphosphate delta-isomerase

G to A

AA 40: S to L