Fig. 1

Reciprocal skin grafts. a Representative image of a recipient mouse with a skin graft, showing a recipient B6-Rhbdf2 ^cub/cub mouse with a skin graft from B6-Rhbdf2 ^+/+ mouse showing retention of hair growth at 12 weeks post-skin graft. b H&E-stained skin section of a female B6-Rhbdf2 ^cub/cub mouse, showing follicular dystrophy (indicated by arrowhead). Scale bar: 50 μm. c H&E-stained skin section of a female B6-Rhbdf2 ^cub/cub mouse with a B6-Rhbdf2 ^+/+ donor skin graft displaying normal hair growth with no evidence of follicular dystrophy (arrows). Scale bar: 50 μm. d H&E-stained skin section of a female B6-Rhbdf2 ^cub/cub mouse with a B6-Rhbdf2 ^cub/cub Areg ^−/− donor skin graft displaying normal hair growth with no evidence of follicular dystrophy (arrows). Scale bar: 50 μm. e H&E-stained skin section of a female B6-Rhbdf2 ^+/+ mouse with a B6-Rhbdf2 ^cub/cub donor skin graft displaying follicular dystrophy (arrowhead); Scale bar: 50 μm. f H&E-stained skin section of a female B6-Rhbdf2 ^cub/cub Areg ^−/− mouse with no skin graft, displaying normal hair growth (arrow). Scale bar: 50 μm. g H&E-stained skin section of a female B6-Rhbdf2 ^cub/cub Areg ^−/− mouse with a B6-Rhbdf2 ^cub/cub donor skin graft, displaying follicular dystrophy (arrowhead). Scale bar: 50 μm