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Table 2 Serum and urinary levels of interleukins at baseline

From: High urinary interleukin-2 in late post-transplant period portends a risk of decline in kidney allograft function: a preliminary study

Interleukins level

Patient groups

eGFR at baseline

eGFR decline by 25% at 2 years

Normal eGFR, ≥ 60 mL/min/1.73 m2 (N = 7)

Low eGFR, < 60 mL/min/1.73 m2 (N = 23)

p

No (N = 23)

Yes (N = 7)

p

IL-8 (pg/mL)

3.00 (1.16–3.87)

3.10 (2.28–5.10)

0.501

3.00 (2.19–3.78)

3.87 (2.30–6.85)

0.360

IL-10 (pg/mL)

2.24 (1.49–3.33)

3.53 (2.24–4.48)

0.061

3.30 (2.24–4.01)

3.87 (1.29–4.55)

0.962

IL-2 (pg/mL)

0.20 (0.16–3.19)

0.20 (0.18–2.34)

0.924

0.64 (0.19–3.19)

0.18 (0.18–0.20)

0.107

IL-8/Cr (pg/mL/mmol/L)

0.21 (0.10–0.39)

0.60 (0.31–2.29)

0.077

0.38 (0.10–0.89)

1.18 (0.21–3.31)

0.190

IL-10/Cr (pg/mL/mmol/L)

0.08 (0.05–0.09)

0.10 (0.07–0.22)

0.118

0.09 (0.07–0.21)

0.08 (0.05–0.17)

0.501

IL-2/Cr (pg/mL/mmol/L)

0.15 (0.06–0.22)

0.25 (0.14–0.74)

0.048

0.20 (0.13–0.36)

0.56 (0.13–2.47)

0.159

  1. IL-2, interleukin 2; IL-8, interleukin 8; IL-10, interleukin 10; Cr, creatinine