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Table 2 Association analysis of rs13334190 in ZNF469 gene with keratoconus

From: Polymorphism rs13334190 in zinc finger protein 469 (ZNF469) is not a risk factor for keratoconus in a Saudi cohort

SNP (gene) rs13334190 (ZNF469)
Allelic analysis Patients (n = 127) No. (%) Controls (n = 168) No. (%) Odds ratio 95% confidence interval p valuea (2-tailed)
G 243 (0.956) 313 (0.931) 1 Reference
Ab 11 (0.043) 23 (0.068) 0.616 0.294–1.288 0.194
HWE p 0.61 0.79
Genotype and model analysis
 G/G 116 (91.3) 146 (86.9) 1 Reference
 G/A 11 (8.6) 21 (12.5) 0.659 0.30–1.42 0.285
 A/A 0 (0) 1 (0.6)
 Additive (trend) 0.387
 Dominant 0.629 0.29–1.35 0.232
  1. aPearson Chi2 test
  2. bRisk variant, HWE p Hardy–Weinberg equilibrium p value