Table 2 Association analysis of rs13334190 in ZNF469 gene with keratoconus
SNP (gene) | rs13334190 (ZNF469) | ||||
|---|---|---|---|---|---|
Allelic analysis | Patients (n = 127) No. (%) | Controls (n = 168) No. (%) | Odds ratio | 95% confidence interval | p valuea (2-tailed) |
G | 243 (0.956) | 313 (0.931) | 1 | Reference | – |
Ab | 11 (0.043) | 23 (0.068) | 0.616 | 0.294–1.288 | 0.194 |
HWE p | 0.61 | 0.79 | – | – | – |
Genotype and model analysis | |||||
G/G | 116 (91.3) | 146 (86.9) | 1 | Reference | – |
G/A | 11 (8.6) | 21 (12.5) | 0.659 | 0.30–1.42 | 0.285 |
A/A | 0 (0) | 1 (0.6) | – | – | – |
Additive (trend) | – | – | – | – | 0.387 |
Dominant | – | – | 0.629 | 0.29–1.35 | 0.232 |