Table 1 Clinical Follow-up of Tg concentrations detected by RIA but undetected/low by EIA or LC MS/MS
Sample# | EIA (ng/mL) | RIA (ng/mL) | LC MS/MS (ng/mL) | Thyroid cancer | Subsequent progression | Subsequent Tg measurements | Months monitored | Imaging |
|---|---|---|---|---|---|---|---|---|
26 | 0 | 2.8 | < 0.4 | PTC | No detectable disease | No change | 24 | Negative |
27 | 0 | 4.1 | < 0.4 | PTC (metastatic) | No progression since 2007 | No change | 24 | Negative—neck only |
28 | 0 | 2.1 | < 0.4 | PTC | No detectable disease | No change | 18 | Negative |
29 | 0 | 2.4 | < 0.4 | PTC | No detectable disease | No change | 14 | Negative |
30 | 0 | 2.3 | < 0.4 | PTC (metastatic) | No detectable disease | No change | 13 | Negative |
31 | 0 | 3 | < 0.4 | PTC | No detectable disease | No change | 17 | Negative |
32 | 0 | 3.2 | < 0.4 | PTC | Recurrence | No change | 11 | No progression |
33 | 0 | 2 | < 0.4 | PTC | No detectable disease | No change | 18 | Negative |
34 | 0.39 | 3.8 | 0.8 | PTC | No detectable disease | No change | 18 | Remnant |
50 | 1.68 | 15 | 3.28 | Graves disease | No follow-up for disease | NA | NA | NA |