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Table 3 Multivariate analysis for LSR reduction of lumber spine and femoral neck BMD

From: Risk factors for bone loss in patients with rheumatoid arthritis treated with biologic disease-modifying anti-rheumatic drugs

Nagelkerke R2: 0.10 Lumber spine
Odds ratio p value
Average dose of prednisolone 1.22 (1.02–1.50) 0.03
Type of anti-osteoporosis drugs 1.52 (0.87–2.65) 0.14
CRP 1.46 (0.95–2.25) 0.08
Nagelkerke R2: 0.08 Femoral neck
Odds ratio p value
Sex 2.37 (0.82–6.90) 0.11
Disease duration 0.95 (0.91–0.10) 0.04
Average dose of prednisolone 1.13 (0.97–1.32) 0.11
  1. The stepwise binomial logistic regression detected high dose of prednisolone use is a risk factors for 12-month LSR of lumbar spine (≤ − 2.4%). The stepwise binomial logistic regression analysis detected short disease duration is a risk factors for 12-month LSR of femoral neck (≤ − 1.9%)
  2. LSR least significant reduction, BMD bone mineral density, CRP serum C-reactive protein concentration
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