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Table 2 ACS subgroups Vs polymorphisms distribution

From: A synergic effect between CYP2C19*2, CYP2C19*3 loss-of-function and CYP2C19*17 gain-of-function alleles is associated with Clopidogrel resistance among Moroccan Acute Coronary Syndromes patients

Cases P value (< 0.05)
CYP2C19*2
681G>A
GG % GA % AA % G allele % A allele % 0.002**
 ST (+) 4 80 16 44 56  
 ST (−) 9.1 84.85 6.06 51.5 48.5  
CYP2C19*3
636G>A
GG % GA % AA % G allele  % A allele % 0.04*
 ST (+) 5.26 73.68 21.06 42.1 57.9  
 ST (−) 3.03 75.76 21.21 40.9 59.1  
CYP2C19*17
− 806 C>T
CC % CT % TT % C allele % T allele % 0.3
 ST (+) 30 50 20 55 45  
 ST (−) 10.87 69.57 19.56 47 53  
  1. ST (+): Acute Coronary Syndromes with ST segment elevation; ST (−): Acute Coronary Syndromes without ST segment elevation
  2. *Statistically significant (Chi square test)