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Table 2 CYP1A1, GSTM1 and GSTT1 genotypes and Green Tobacco Sickness (GTS)

From: Green Tobacco Sickness among Brazilian farm workers and genetic polymorphisms

Genotypes All workers N = 167 (%) GTS yes
N = 95 (%)
GTS no
N = 72 (%)
p value
CYP1A1 (m1 −) 104 (62.3) 60 (63.2) 44 (61.1) 0.872
CYP1A1 (m1 +) 63 (37.7) 35 (36.8) 28 (38.9)  
CYP1A1 (m2 −) 38 (22.8) 22 (23.2) 16 (22.2) 1.000
CYP1A1 (m2 +) 129 (77.2) 73 (76.8) 56 (77.8)  
GSTM1 present 89 (53.3) 55 (57.9) 34 (47.2) 0.210
GSTM1 null 78 (46.7) 40 (42.1) 38 (52.8)  
GSTT1 present 130 (78.0) 70 (73.7) 60 (83.3) 0.187
GSTT1 null 37 (22.0) 25 (26.3) 12 (16.7)  
  1. m1  no m1 polymorphism, m1 + m1 polymorphism
  2. m2  no m2 polymorphism; m2 + m2 polymorphism
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