Table 2 CYP1A1, GSTM1 and GSTT1 genotypes and Green Tobacco Sickness (GTS)
From: Green Tobacco Sickness among Brazilian farm workers and genetic polymorphisms
Genotypes | All workers N = 167 (%) | GTS yes N = 95 (%) | GTS no N = 72 (%) | p value |
|---|---|---|---|---|
CYP1A1 (m1 −) | 104 (62.3) | 60 (63.2) | 44 (61.1) | 0.872 |
CYP1A1 (m1 +) | 63 (37.7) | 35 (36.8) | 28 (38.9) | |
CYP1A1 (m2 −) | 38 (22.8) | 22 (23.2) | 16 (22.2) | 1.000 |
CYP1A1 (m2 +) | 129 (77.2) | 73 (76.8) | 56 (77.8) | |
GSTM1 present | 89 (53.3) | 55 (57.9) | 34 (47.2) | 0.210 |
GSTM1 null | 78 (46.7) | 40 (42.1) | 38 (52.8) | |
GSTT1 present | 130 (78.0) | 70 (73.7) | 60 (83.3) | 0.187 |
GSTT1 null | 37 (22.0) | 25 (26.3) | 12 (16.7) |