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Table 1 The Sequential Organ Failure Assessment (SOFA) score

From: Increased whole blood FFA2/GPR43 receptor expression is associated with increased 30-day survival in patients with sepsis

Variable

SOFA score

0

1

2

3

4

Respiratory

 Pa02/Fi02 mmHg

> 400

< 400

< 300

< 200

< 100a

Coagulation

 Platelets × 103/μL

> 150

< 150

< 100

< 50

< 20

Liver

 Bilirubin, mg/dL

< 1.2

1.2–1.9

2.0–5.9

6.0–11.9

> 12.0

Cardiovascular

 Hypotension

No hypotension

Mean arterial pressure < 70

Dop < 5 or Dob any doseb

Dop > 5, Epi < 0.1 or Norepi < 0.1b

Dop > 15, Epi > 0.1, Norepi > 0.1b

Central nervous system

 Glasgow coma scale

15

13–14

10–12

6–9

< 6

Renal

 Creatinine, mg/dL or urine output, mL/day

< 1.2

1.2–1.9

2.0–3.4

3.5–4.9 or < 500

> 5.0 or < 200

  1. Norepi indicates norepinephrine, Dob dobutamine, Dop dopamine, Epi epinephrine, Fi02 fraction of inspired oxygen
  2. aWith respiratory support
  3. bAdrenergic agents administered for at least 1 h (doses in µg/kg/min)