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Table 1 The Sequential Organ Failure Assessment (SOFA) score

From: Increased whole blood FFA2/GPR43 receptor expression is associated with increased 30-day survival in patients with sepsis

Variable SOFA score
0 1 2 3 4
Respiratory
 Pa02/Fi02 mmHg > 400 < 400 < 300 < 200 < 100a
Coagulation
 Platelets × 103/μL > 150 < 150 < 100 < 50 < 20
Liver
 Bilirubin, mg/dL < 1.2 1.2–1.9 2.0–5.9 6.0–11.9 > 12.0
Cardiovascular
 Hypotension No hypotension Mean arterial pressure < 70 Dop < 5 or Dob any doseb Dop > 5, Epi < 0.1 or Norepi < 0.1b Dop > 15, Epi > 0.1, Norepi > 0.1b
Central nervous system
 Glasgow coma scale 15 13–14 10–12 6–9 < 6
Renal
 Creatinine, mg/dL or urine output, mL/day < 1.2 1.2–1.9 2.0–3.4 3.5–4.9 or < 500 > 5.0 or < 200
  1. Norepi indicates norepinephrine, Dob dobutamine, Dop dopamine, Epi epinephrine, Fi02 fraction of inspired oxygen
  2. aWith respiratory support
  3. bAdrenergic agents administered for at least 1 h (doses in µg/kg/min)