TY - JOUR AU - Misawa, Kazuhisa AU - Tarumoto, Norihito AU - Tamura, Shinsuke AU - Osa, Morichika AU - Hamamoto, Takaaki AU - Yuki, Atsushi AU - Kouzaki, Yuji AU - Imai, Kazuo AU - Ronald, Runtuwene Lucky AU - Yamaguchi, Toshiyuki AU - Murakami, Takashi AU - Maesaki, Shigefumi AU - Suzuki, Yutaka AU - Kawana, Akihiko AU - Maeda, Takuya PY - 2018 DA - 2018/01/20 TI - Single nucleotide polymorphisms in genes encoding penicillin-binding proteins in β-lactamase-negative ampicillin-resistant Haemophilus influenzae in Japan JO - BMC Research Notes SP - 53 VL - 11 IS - 1 AB - β-Lactamase-negative ampicillin-resistant Haemophilus influenzae is a common opportunistic pathogen of hospital- and community-acquired infections, harboring multiple single nucleotide polymorphisms in the ftsI gene, which codes for penicillin-binding protein-3. The objectives of this study were to perform comprehensive genetic analyses of whole regions of the penicillin-binding proteins in H. influenzae and to identify additional single nucleotide polymorphisms related to antibiotic resistance, especially to ampicillin and other cephalosporins. SN - 1756-0500 UR - https://doi.org/10.1186/s13104-018-3169-0 DO - 10.1186/s13104-018-3169-0 ID - Misawa2018 ER -