Table 3 Association of clinicopathological and prognostic parameters of colorectal carcinoma with N stage
Variable | N stage | P value | |||
|---|---|---|---|---|---|
N0 | N1 | N2a | N2b | ||
Age (years) | |||||
< 50 | 10 | 8 | 9 | 10 | 0.19 |
> 50 | 22 | 22 | 10 | 9 | |
Gender | |||||
Male | 18 | 13 | 10 | 10 | 0.777 |
Female | 14 | 17 | 9 | 9 | |
Laterality | |||||
Right | 6 | 11 | 5 | 8 | 0.26 |
Left | 26 | 19 | 14 | 11 | |
Lymphovascular invasion | |||||
Present | 0 | 8 | 9 | 10 | < 0.001* |
Absent | 32 | 22 | 10 | 9 | |
Grade | |||||
Well differentiated | 3 | 0 | 0 | 0 | < 0.001* |
Moderately differentiated | 27 | 26 | 16 | 7 | |
Poorly differentiated | 2 | 4 | 3 | 12 | |
Tumor type | |||||
Adenocarcinoma, NOS | 29 | 27 | 16 | 8 | 0.006* |
Mucinous carcinoma | 2 | 2 | 2 | 7 | |
Medullary carcinoma | 1 | 0 | 0 | 1 | |
Signet ring cell carcinoma | 0 | 1 | 1 | 3 | |
Perinodal spread | |||||
Present | 0 | 13 | 15 | 19 | < 0.001* |
Absent | 32 | 17 | 4 | 0 | |
Mucinous histology (%) | |||||
Absent | 26 | 20 | 15 | 7 | 0.006* |
< 10 | 2 | 6 | 2 | 2 | |
10–50 | 3 | 0 | 0 | 4 | |
> 50 | 1 | 4 | 2 | 6 | |
Signet ring differentiation | |||||
Present | 1 | 5 | 2 | 8 | 0.003* |
Absent | 31 | 25 | 17 | 11 | |
Medullary differentiation | |||||
Present | 1 | 0 | 0 | 0 | 0.543 |
Absent | 31 | 30 | 19 | 19 | |
Necrosis | |||||
Absent | 1 | 2 | 3 | 0 | 0.097 |
Focal | 22 | 20 | 10 | 18 | |
Widespread | 9 | 8 | 6 | 1 | |
Tumor infiltrating lymphocytes | |||||
None | 14 | 15 | 13 | 16 | 0.019* |
Mild-moderate | 7 | 9 | 5 | 3 | |
Marked | 11 | 6 | 1 | 0 | |
Peri-tumoral lymphocytes | |||||
None | 21 | 24 | 12 | 10 | 0.639 |
Mild-moderate | 6 | 3 | 4 | 5 | |
Marked | 5 | 3 | 3 | 4 | |
Pre-existing polyp | |||||
Present | 7 | 2 | 1 | 0 | 0.047* |
Absent | 25 | 28 | 18 | 19 | |