Minimum values for midluteal plasma progesterone and estradiol concentrations in patients who achieved pregnancy with timed intercourse or intrauterine insemination without a human menopausal gonadotropin

Table 2 Subgroup analyses in pregnant cycles

	Letrozole	Cyclofenil	Clomifene	No medication	P value
	(n = 26)	(n = 75)	(n = 132)	(n = 64)	P value
Age (years)*	31.2 ± 3.0^ab	33.8 ± 3.9	33.9 ± 4.0	33.4 ± 4.2	< 0.01
BMI (kg/m²)*	20.5 ± 3.6	20.4 ± 2.4	21.1 ± 2.8	20.4 ± 2.9	NS
P4 (ng/mL)
Mean*	12.8 ± 4.1	12.0 ± 5.9^a	17.2 ± 9.0	12.8 ± 5.4^c	< 0.01
Median	12.9	11.1	15.4	11.9	NA
5‰ P4	5.9	4.8	6.6	5.8	NA
Lowest P4	4.6	2.3	3.7	5.0	NA
E2 (pg/mL)
Mean*	127.7 ± 84.6^a	146.9 ± 80.6^a	241.8 ± 138.7	149.5 ± 56.9^a	< 0.01
Median	106.8	133.1	203.3	140.1	NA
5‰	28.2	59.9	93.3	71.3	NA
Lowest E2	23.4	44.2	70.2	71.1	NA

NS not significant, NA not available
* Values are indicated by means ± standard deviations. The Kruskal–Wallis H-test (two-sided) was used for comparisons among the four groups
^aThe Mann–Whitney U-test (two-sided) was used for comparisons between the two groups compared with clomifene group (P < 0.01)
^bThe Mann–Whitney U-test (two-sided) was used for comparisons between the two groups compared with cyclofenil group (P < 0.05)
^cThe Mann–Whitney U-test (two-sided) was used for comparisons between the two groups compared with clomifene group (P < 0.05)

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