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Table 1 Summarization of histopathology results for spleen and liver biopsies

From: Histopathologic characteristics of biopsies from dogs undergoing surgery with concurrent gross splenic and hepatic masses: 125 cases (2012–2016)

Splenic biopsies obtained in the study No. (% of total) No. (% of 125 dogs)
Malignant splenic lesions
Hemangiosarcoma 69 (82.1) 69 (55.2)
Leiomyosarcoma 4 (4.8) 4 (3.2)
Histiocytic sarcoma 3 (3.6) 3 (2.4)
Undifferentiated sarcoma 2 (2.4) 2 (1.6)
Anaplastic spindle cell sarcoma 1 (1.2) 1 (0.8)
Stromal sarcoma 1 (1.2) 1 (0.8)
Osteosarcoma 1 (1.2) 1 (0.8)
Mast cell tumor 1 (1.2) 1 (0.8)
Liposarcoma 1 (1.2) 1 (0.8)
Lymphosarcoma 1 (1.2) 1 (0.8)
Total No. malignant splenic lesions (%) 84 (100)a 84 (67.2)a
Benign splenic lesions
Nodular hyperplasia 27 (43.5) 27 (21.6)
Hematoma 11 (17.7) 11 (8.8)
 Infarct 5 (8.1) 5 (4)
Extramedullary hematopoiesis 4 (6.5) 4 (3.2)
Myelolipoma 3 (4.8) 3 (2.4)
Plaques 3 (4.8) 3 (2.4)
Necrosis 2 (3.2) 2 (1.6)
Splenitis 2 (3.2) 2 (1.6)
Congestion 2 (3.2) 2 (1.6)
Lipoma 1 (1.6) 1 (0.8)
Lymphoid hyperplasia 1 (1.6) 1 (0.8)
Hemosiderosis 1 (1.6) 1 (0.8)
Total No. benign splenic lesions (%) 62 (100)a 62 (49.6)a
Liver biopsies obtained in the study No. (% of total) No. (% of 125 dogs)
Malignant liver lesions
Hemangiosarcoma 51 (75) 51 (40.8)
Hepatocellular carcinoma 4 (5.9) 4 (3.2)
Histiocytic sarcoma 3 (4.4) 3 (2.4)
Leiomyosarcoma 3 (4.4) 3 (2.4)
Lymphosarcoma 2 (2.9) 2 (1.6)
Undifferentiated sarcoma 2 (2.9) 2 (1.6)
Anaplastic spindle cell sarcoma 1 (1.5) 1 (0.8)
Liposarcoma 1 (1.5) 1 (0.8)
Stromal sarcoma 1 (1.5) 1 (0.8)
Total No. malignant liver lesions (%) 68 (100)a 68 (54.4)a
Benign liver lesions
Nodular hyperplasia 26 (37.7) 26 (20.8)
Hydrophic vacuolar hepatopathy 16 (23.2) 16 (12.8)
Hepatoma 6 (8.7) 6 (4.8)
Hepatitis 4 (5.8) 4 (3.2)
Cholangiohepatitis 2 (2.9) 2 (1.6)
Fibrosis 2 (2.9) 2 (1.6)
Lymphoplasmacytic hepatitis 2 (2.9) 2 (1.6)
Necrosis 2 (2.9) 2 (1.6)
Cirrhosis 2 (2.9) 2 (1.6)
Extramedullary hematopoiesis 1 (1.4) 1 (0.8)
Hematoma 1 (1.4) 1 (0.8)
Lipogranuloma 1 (1.4) 1 (0.8)
Lymphohistiocytic hepatitis 1 (1.4) 1 (0.8)
Congestion 1 (1.4) 1 (0.8)
Infarct 1 (1.4) 1 (0.8)
Cholestasis 1 (1.4) 1 (0.8)
Total No. benign liver lesions (%) 69 (100)a 69 (55.2)a
  1. aSome dogs had multiple lesions on histopathology, thus absolute numbers and percentages do not add up to 125 and 100% respectively