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Table 1 Evaluation of different quality control parameter of esomeprazole [10, 18, 20, 21]

From: In vitro comparative quality evaluation of different brands of esomeprazole tablets available in selected community pharmacies in Dhaka, Bangladesh

Sample Weight variation (%)a Hardness (Kgf)b Disintegration (Min)c Potency (%)d
(Mean ± % RSD)
E01 1.20 ± 0.23 5.32 ± 0.06 29.05 ± 0.14 95.28 ± 0.08
E02 1.41 ± 0.54 6.71 ± 0.02 26.83 ± 0.09 98.45 ± 0.16
E03 2.01 ± 0.14 5.76 ± 0.14 19.93 ± 0.04 99.40 ± 0.11
E04 1.01 ± 0.29 6.26 ± 0.09 26.28 ± 0.18 98.63 ± 0.13
E05 1.21 ± 0.42 7.12 ± 0.12 28.18 ± 0.02 98.87 ± 0.06
USP specification NMT ± 5% to ± 7.5% 4–8 kgf 5–30 min 95–105%
  1. a20 time replication for each brand
  2. b10 time replication for each brand
  3. c6 time replication for each brand
  4. d3 time replication for each brand