TY - JOUR AU - Noury, Amr El AU - Azmy, Osama AU - Alsharnoubi, Jehan AU - Salama, Sameh AU - Okasha, Ahmed AU - Gouda, Weaam PY - 2018 DA - 2018/03/15 TI - Variants of CDKAL1 rs7754840 (G/C) and CDKN2A/2B rs10811661 (C/T) with gestational diabetes: insignificant association JO - BMC Research Notes SP - 181 VL - 11 IS - 1 AB - Pathophysiological similarity exists between gestational diabetes mellitus (GDM) and type 2 diabetes mellitus with common genetic origin. Genetic liability for GDM in our population is still not researched. The goal was to reveal the genotypic and allele frequency differences of 2 single nucleotide polymorphisms (SNPs) namely, CDKAL1 (rs7754840) and CDKN2A/2B (rs10811661) between GDM pregnancies and normal pregnancies. We assessed them by real time polymerase chain reaction using Taqman® allelic discrimination assays. We included 47 GDM pregnant subjects and 51 normal glucose tolerance (NGT) pregnant women as controls. SN - 1756-0500 UR - https://doi.org/10.1186/s13104-018-3288-7 DO - 10.1186/s13104-018-3288-7 ID - Noury2018 ER -