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Table 2 Comparison of genotype frequencies between GDM cases and NGT group

From: Variants of CDKAL1 rs7754840 (G/C) and CDKN2A/2B rs10811661 (C/T) with gestational diabetes: insignificant association

Gene/allele

SNP

Genotype

GDM

NGT

P

P value

OR (95% CI)

CDKAL1

Genotype

rs7754840

GG/GC/CC

3/26/18

(6.4/55.3/38.3)

8/23/20

(15.7/45.1/39.2)

 

0.301

 

GG

3 (6.4)

8 (15.7)

0.132

  

GC

26 (55.3)

23 (45.1)

0.184

  

CC

18 (38.3)

20 (39.2)

0.746

  

Allele

C

62 (66)

63 (61.8)

 

0.542

1.199 (0.669–2.152)

G

32 (34)

39 ( 38.2)

   

CDKN2A/B

Genotype

rs1081166

CC/CT/TT

38/7/2

(74.5/14.9/4.3)

38/10/3

(80.9/19.6/5.9)

 

0.753

 

CC

38 (74.5)

38 (80.9)

1.00

  

CT

7 (14.9)

10 (19.6)

0.467

  

TT

2 (4.3)

3 (5.9)

0.655

  

Allele

T

11 (11.7)

16 (15.7)

 

0.419

0.712 (0.312–1.625)

C

83 (88.3)

86 (84.3