Skip to main content

Advertisement

Table 2 Comparison of genotype frequencies between GDM cases and NGT group

From: Variants of CDKAL1 rs7754840 (G/C) and CDKN2A/2B rs10811661 (C/T) with gestational diabetes: insignificant association

Gene/allele SNP Genotype GDM NGT P P value OR (95% CI)
CDKAL1 Genotype rs7754840 GG/GC/CC 3/26/18 (6.4/55.3/38.3) 8/23/20 (15.7/45.1/39.2)   0.301  
GG 3 (6.4) 8 (15.7) 0.132   
GC 26 (55.3) 23 (45.1) 0.184   
CC 18 (38.3) 20 (39.2) 0.746   
Allele C 62 (66) 63 (61.8)   0.542 1.199 (0.669–2.152)
G 32 (34) 39 ( 38.2)    
CDKN2A/B Genotype rs1081166 CC/CT/TT 38/7/2 (74.5/14.9/4.3) 38/10/3 (80.9/19.6/5.9)   0.753  
CC 38 (74.5) 38 (80.9) 1.00   
CT 7 (14.9) 10 (19.6) 0.467   
TT 2 (4.3) 3 (5.9) 0.655   
Allele T 11 (11.7) 16 (15.7)   0.419 0.712 (0.312–1.625)
C 83 (88.3) 86 (84.3