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Table 3 Logistic regression of distributions and genetic models of each SNP’s genotype of CDKAL1 and CDKN2A/B

From: Variants of CDKAL1 rs7754840 (G/C) and CDKN2A/2B rs10811661 (C/T) with gestational diabetes: insignificant association

 

GDM, n (%)

None GDM, n (%)

P value

OR (95% CI)

rs7754840 (CDKAL1)

Co-dominant model

G/G

3 (6.4)

8 (15.7)

 

1

C/G

26 (55.3)

23 (45.1)

0.122

3.014 (0.714–12.731)

C/C

18 (38.3)

20 (39.2)

0.236

2.400 (0.551–10.457)

 Dominant model

CG + CC

44 (93.6)

43 (84.3)

0.145

2.729 (0.678–10.976)

GG

3 (6.4)

8 (15.7)

1

 Recessive model

CC

18 (38.3)

20 (39.2)

0.926

0.962 (0.426–2.170)

GG + CG

29 (61.7)

31 (60.8)

1

Over-dominant model

CG

26 (55.3)

23 (45.1)

0.312

1.507 (0.679–3.344)

GG + CC

21 (44.7)

28 (54.9)

1

rs10811661(CDKN2A/B)

Co-dominant model

CC

38 (80.9)

38 (74.5)

 

1

CT

7 (14.9)

10 (19.6)

0.510

0.700 (0.241–2.031)

TT

2 (4.3)

3 (5.9)

0.665

0.667 (0.105–4.218)

 Dominant model

CT + TT

9 (19.1)

13 (25.5)

0.452

0.692 (0.265–1.811)

CC

38 (80.9)

38 (74.5)

1

 Recessive model

TT

2 (4.3)

3 (5.9)

0.715

0.711 (0.114–4.454)

CC + CT

45 (95.7)

48 (94.1)

1

Over-dominant model

CT

7 (14.9)

10 (19.6)

0.538

0.718 (0.249–2.070)

CC + TT

40 (85.1)

41 (80.4)

1