Table 2 Association of CK 5/6 expression with clinicopathologic features of bladder cancer
| Â | CK 5/6 n (%) | P value | |||
|---|---|---|---|---|---|
Positive | Negative | Focal positive | Total | ||
Gender | |||||
 Male | 8 (100) | 77 (75.5) | 8 (47.1) | 93 (73.2) | 0.014 |
 Female | 0 (0) | 25 (24.5) | 9 (52.9) | 34 (26.8) | |
 Total | 8 | 102 | 17 | 127 |  |
Age group | |||||
 ≤ 25 years | 0 (0) | 1 (1) | 0 (0) | 1 (0.8) | 0.613 |
 26–50 years | 2 (25) | 26 (25.5) | 2 (11.8) | 30 (23.6) | |
 > 50 years | 6 (75) | 75 (73.5) | 15 (88.2) | 96 (75.6) | |
 Total | 8 | 102 | 17 | 127 |  |
Tissue type | |||||
 Transurethral resection | 6 (75) | 99 (97.1) | 17 (100) | 122 (96.1) | 0.049 |
 Radical cystectomy | 2 (25) | 3 (2.9) | 0 (0) | 5 (3.9) | |
 Total | 8 | 102 | 17 | 127 |  |
Tumor grade | |||||
 Low grade | 0 (0) | 59 (57.8) | 5 (29.4) | 64 (50.4) | 0.000 |
 High grade | 8 (100) | 43 (42.2) | 12 (70.6) | 63 (49.6) | |
Total | 8 | 102 | 17 | 127 | Â |
Lamina propria invasion | |||||
 Present | 5 (62.5) | 31 (30.4) | 3 (17.6) | 39 (30.7) | 0.081 |
 Absent | 3 (37.5) | 71 (69.6) | 14 (82.4) | 88 (69.3) | |
 Total | 8 | 102 | 17 | 127 |  |
Deep muscle invasion | |||||
 Present | 5 (62.5) | 19 (18.6) | 2 (11.8) | 26 (20.5) | 0.049 |
 Absent | 1 (12.5) | 47 (46.1) | 10 (58.8) | 58 (45.7) | |
 Can’t assessed | 2 (25) | 36 (35.3) | 5 (29.4) | 43 (33.9) | |
 Total | 8 | 102 | 17 | 127 |  |
Recurrence (n = 54) | |||||
 Yes | 2 (50) | 18 (40) | 2 (40) | 22 (40.7) | 1.000 |
 No | 2 (50) | 27 (60) | 3 (60) | 32 (59.3) | |
 Total | 4 | 45 | 5 | 54 |  |
Survival status (n = 54) | |||||
 Alive | 3 (75) | 39 (86.7) | 5 (100) | 47 (87) | 0.514 |
 Expired | 1 (25) | 6 (13.3) | 0 (0) | 7 (13) | |
 Total | 4 | 45 | 5 | 54 |  |