Anti-plasmodial activities of Combretum molle (Combretaceae) [Zwoo] seed extract in Swiss albino mice

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Table 1 Percent parasitemia, percent parasite suppression and mean survival time of mice infected with PbA and treated with seed crude extracts of C. molle

Groups	Anti-malarial activities of the extract on day 4 p.i.		Survival time (mean day ± SD)
Groups	% parasitemia (mean ± SD)	% parasite suppression/inhibition	Survival time (mean day ± SD)
Control	35.7 ± 1.51	0.0	9.5 ± 0.29
125	26.9 ± 1.88^a1	36.6 ± 2.72^a2	10.5 ± 0.11
250	15.5 ± 1.9^a2	63.5 ± 3.49^a1	12^a ± 0.56
CQ	6.28 ± 0.27^b3	85.23 ± 0.04^b2	> 30

NB: ^a compared to control, ^b compared to chloroquine (CQ) treated (10 mg/kg); ¹ P < 0.05; ² P < 0.01, ³ P < 0.001
CON control, p.i. post-infection

ISSN: 1756-0500