From: Spontaneous splenic rupture complicating primary varicella zoster infection: a case report
A) Blood results: | |||||
Haemoglobin | 110 g/l | CRP | 59 mg/l | Malaria parasites | None seen |
MCV | 91.3 fl | Bilirubin | 26 μmol/l | EBV VCA IgG | Negative |
Platelets | 78 × 109/l | Alkaline phosphatase | 27 IU/l | EBV VCA IgM | Negative |
White cell count | 3.6 × 109/l | Alanine aminotransferase | 27 IU/l | EBV EBNA IgG | Positive |
Neutrophils | 2.4 × 109/l | Albumin | 35 g/l | CMV IgG | Positive |
Lymphocytes | 0.6 × 109/l | Sodium | 134 mmol/l | CMV IgM | Negative |
Eosinophils | 0.0 × 109/l | Potassium | 4.4 mmol/l | HIV-1 and 2 | Non reactive |
Blood film | Thrombocytopenia. Stomatocytes seen | Urea | 7.8 mmol/l | Hep B surface antigen | Non reactive |
INR | 1.0 | Creatinine | 70 μmol/l | Hep B core antibody | Negative |
Prothrombin time | 11.4 s | Amylase | 33 IU/l | Hep C antibody | Negative |
APTT | 33.0 s | Lactate | 1.2 | Urine Chlamydia DNA | Negative |
APTT ratio | 1.10 | Bicarbonate | 24 | VZV IgG | Equivocal |
B) Vesicle fluid investigations | |||||
VZV DNA | Detected | ||||
HSV DNA | Not detected | ||||
C) Histology report summary | |||||
Spleen shows normal histology with subcapsular haematoma and a minor degree of intraparenchymal haemorrhage. The splenic white pulp and red pulp appear normal. No granulomas are seen, there is no evidence of a neoplastic process. In situ hybridisation for EBV is negative and Congo red stains for amyloid deposition is also negative |