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Table 1 Susceptibility of intracellular amastigotes of L. major and L. donovani towards the respective drugs, represented by EC50 values

From: In vitro screening of known drugs identified by scaffold hopping techniques shows promising leishmanicidal activity for suramin and netilmicin

Serial no.

Drug/compound

EC50 ± SD (µM)

5ASKHa

AG83b

1

Primaquine

11.8 ± 0.8

6.0 ± 1.2

2

Paromomycin

7.5 ± 2.3

8.4 ± 3.3

3

Netilmicin

12.3 ± 2.3

8.6 ± 1.4

4

Suramin

4.6 ± 0.8

4.1 ± 0.3

5

Curcumin

8.1 ± 1.1

12.6 ± 1.5

  1. Results are given as mean ± SD of three independent experiments
  2. aL. major; b L. donovani
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BMC Research Notes

ISSN: 1756-0500

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