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Fig. 1 | BMC Research Notes

Fig. 1

From: Prevention of haematoma progression by tranexamic acid in intracerebral haemorrhage patients with and without spot sign on admission scan: a statistical analysis plan of a pre-specified sub-study of the TICH-2 trial

Fig. 1

The spot sign is generally understood to be a radiological visualisation of an actively bleeding ruptured blood vessel (b) causing intraparenchymal haematoma expansion and by extension expansion of the intraventricular haematoma (a). The actively bleeding ruptured vessel is visualised on CT-angiography as the spot sign. c Depicts an authentic CT-angiography image of an acute intracerebral haemorrhage patient. A relatively large spot sign can be observed within the haematoma. Significantly enlarged intraparenchymal and intraventricular haematomas can often be seen on follow-up imaging (d)

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